First order kinetics

Which of the following is true for a drug whose elimination from plasma shows first order kinetics?

A. The half life of the drug is proportional to the drug concentration in plasma.

B. the amount eliminated per unit of time is constant.

C. the rate of elimination is proportional to the plasma concentration

D. elimination involves a rate limiting enzymatic reaction operating at its maximum velocity

E. a plot of drug concentration vs time is a straight line

Answer